London, United Kingdom: Daniel Sturridge served a reminder of his worth to Liverpool manager Jurgen Klopp with both goals in a 2-1 victory over Tottenham Hotspur in England'sLeague Cup on Tuesday.

Sturridge has started three of Liverpool's last four Premier League games on the bench, but he seized his chance at Anfield to send last season's beaten finalists into the quarter-finals.

Arsenal also progressed, Alex Oxlade-Chamberlain scoring twice in a 2-0 win over Reading, while Hull City won 2-1 at second-tier Bristol City.

Klopp and Spurs counterpart Mauricio Pochettino between them made 21 changes to their starting line-ups, with visiting midfielder Eric Dier the only player to keep his place from the weekend fixtures.

Klopp gave a debut to 18-year-old right-back Trent Alexander-Arnold and a full debut to midfielder Ovie Ejaria, 19, while 18-year-old Cameron Carter-Vickers started at centre-back for Tottenham.

Liverpool, who lost on penalties to Manchester City in last season's final, took a ninth-minute lead when Marko Grujic's deflected cross from the right was stabbed in by Sturridge.

Spurs stand-in goalkeeper Michel Vorm repelled long-range efforts from Sturridge and Divock Origi before Georginio Wijnaldum freed the England striker to score his second goal in the 64th minute.

Dutch striker Vincent Janssen reduced the arrears with a 76th-minute penalty after Lucas Leiva took an unnecessary nibble at Tottenham substitute Erik Lamela.

But it was the home side who came closest to scoring again, with Vorm saving spectacularly from Sturridge and substitute Danny Ings.

Arsenal joined Klopp's men in the last eight after seeing off second-tier Reading, who are managed by former Manchester United defender Jaap Stam.

Oxlade-Chamberlain struck twice for Arsene Wenger's much-changed team, drilling home in the 33rd minute and netting again with the aid of a deflection with 12 minutes to play.

Headers from centre-backs Harry Maguire and Michael Dawson took Hull through at the expense of Bristol City, who replied through Lee Tomlin's 50-yard solo goal in stoppage time.

Aleksandar Mitrovic and Mohamed Diame each scored twice as Championship leaders Newcastle United routed 10-man Preston North End 6-0 at St James' Park.

The tie of the round takes place on Wednesday, when Jose Mourinho and Pep Guardiola resume hostilities as Manchester United tackle Manchester City at Old Trafford.

Chelsea visit London rivals West Ham United and Southampton host the Premier League's bottom club, Sunderland.